Twitter applications such as Tweetdeck and seesmic are much better than using the twitter web page. Applications such as these allow for much greater functionality. For instance, Tweetdeck (which seems to be the favourite lately) gives you a subject and keyword filter, thus separating information of interest. The AdobeAIR application has support for integrating your acebook account as well.

It has in-built features like TwitPic (a way of sharing pictures on twitter), url shortening and translation mols. You can of course also send out updates from here as well.